Fiery Last-Lap Daytona Crash Injures 28 Fans

A fiery last-lap crash at the Daytona International Speedway injured a number of spectators today, who were seen being carried away from the stands on stretchers.

A total of 28 fans were injured, with 14 transported to hospitals and 14 treated at the speedway, Dayton president Joie Chitwood III. All the drivers involved in the crash have been treated and released, Chitwood said.

ESPN reported that one of the spectators taken to the hospital was on the way to surgery with head trauma.

The 12-car crash happened moments before the end of the Nationwide race, and on the eve of the Daytona 500, one of NASCAR's biggest events.

The crash was apparently triggered when driver Regan Smith's car, which was being tailed by Brad Keselowski on his back bumper, spun to the right and shot up the track. Smith had been in the lead and said after the crash he had been trying to throw a "block."

PHOTOS: Crash at Daytona Sends Wreckage Into Stands

Rookie Kyle Larson's car slammed into the wall that separates the track from the grandstands, causing his No. 32 car to go airborne and erupt in flames.

When a haze of smoke cleared and Larson's car came to a stop, he jumped out uninjured.

His engine and one of his wheels were sitting in a walkway of the grandstand.

"I was getting pushed from behind," Larson told ESPN. "Before I could react, it was too late."

Tony Stewart pulled out the win, but in victory lane, what would have been a celebratory mood was tempered by concern for the injured fans.

"We've always known this is a dangerous sport," Stewart said. "But it's hard when the fans get caught up in it."

Repairs are under way on the fence where the crash happened and are expected to be completed before the Daytona 500 on Sunday, Chitwood said.

He told reporters NASCAR does not anticipate having to move any of their fans for the Daytona 500 and expects all seats will be filled.

Read More..

Italians head to polls in crucial vote for euro zone

ROME (Reuters) - Italians vote on Sunday in one of the most closely watched elections in years with markets nervous about whether it will produce a strong government to pull Italy out of recession and help resolve the euro zone debt crisis.

A huge final rally by anti-establishment-comedian-turned-politician Beppe Grillo on Friday before a campaigning ban kicked in has highlighted public anger at traditional parties and added to uncertainty about the election outcome.

Polling booths will open between 02:00 am-04:00 pm EST on Sunday and 01:00 am-09:00 am EST on Monday. Exit polls will come out soon after voting ends and official results are expected by early Tuesday.

The election will be followed closely by financial markets with memories still fresh of the potentially catastrophic debt crisis that brought technocrat Prime Minister Mario Monti to power more than a year ago.

Italy, the euro zone's third-largest economy, is stuck in deep recession, struggling under a public debt burden second only to Greece's in the 17-member currency bloc and with a public weary of more than a year of harsh austerity policies.

Italy's Interior Ministry has urged some 47 million eligible voters to not let bad weather forecasts put them off, and said it was prepared to handle even snowy conditions in some northern regions to ensure everyone had a chance to vote.

Final polls published two weeks ago showed center-left leader Pier Luigi Bersani with a five-point lead, but analysts disagree about whether he will be able to form a stable majority that can push though the economic reforms Italy needs.

Bersani is now thought to be just a few points ahead of center-right rival Silvio Berlusconi, the four-times prime minister who has promised tax refunds and staged a media blitz in an attempt to win back voters in recent weeks.

While the center left is still expected to gain control of the lower house thanks to rules that guarantee a strong majority to whichever party wins the most votes nationally, a much closer battle will be fought in the Senate, which any government also needs to control in order to be able to pass laws.

Seats in the upper house are awarded on a region-by-region basis, meaning that support in key regions can decisively influence the overall result.

Pollsters still believe the most likely outcome is a center-left government headed by Bersani and possibly backed by Monti, who is leading a centrist coalition.

But strong campaigning by Berlusconi and the fiery Grillo, who has drawn tens of thousands to his election rallies, have thrown the election wide open, causing concern that there may be no clear winner.

Whatever government emerges from the vote will have the task of pulling Italy out of its longest recession for 20 years and reviving an economy largely stagnant for two decades.

The main danger for Italy and the euro zone is a weak government incapable of taking firm action, which would rattle investors and could ignite a new debt crisis.

Monti replaced Berlusconi in November 2011 after the euro zone's third-largest economy came close to Greek-style financial meltdown while the center-right government was embroiled in scandals.

The former European Commissioner launched a tough program of spending cuts, tax hikes and pension reforms which won widespread international backing and helped restore Italy's credibility abroad after the scandals of the Berlusconi era.

Italy's borrowing costs have since fallen sharply after the European Central Bank pledged it was prepared to support countries undertaking reforms by buying unlimited quantities of their bonds on the markets.

But economic austerity has fuelled anger among Italians grappling with rising unemployment and shrinking disposable incomes, encouraging many to turn to Grillo, who has tapped into a national mood of disenchantment.

(Reporting by Catherine Hornby; Editing by Jason Webb)

Read More..

Britain's top Catholic in 'inappropriate acts' row: report

LONDON: Britain's most senior Roman Catholic cleric, who is due to vote on Pope Benedict XVI's successor, has been reported to the Vatican over claims of inappropriate behaviour, the Observer reported on Sunday.

Cardinal Keith O'Brien, leader of the Catholic Church in Scotland, contests allegations by three priests and a former priest which were sent to Rome a week before Pope Benedict's resignation on February 11.

The four claimants, from the diocese of St Andrews and Edinburgh in Scotland, reported to nuncio Antonio Mennini, the Vatican's ambassador to Britain, that O'Brien had committed "inappropriate acts" going back 33 years.

One priest claims he received unwanted attention from the cardinal after a late-night drinking session. Another alleges that O'Brien used night prayers as cover for inappropriate contact, according to the paper.

O'Brien has a vote in the forthcoming papal conclave.

The claimants, who are demanding the cleric's resignation, are worried that their report will not be properly addressed if he is allowed to travel to Rome.

"It (the church) tends to cover up and protect the system at all costs," said one of the complainants, according to quotes published by the Observer newspaper.

"The church is beautiful, but it has a dark side and that has to do with accountability. If the system is to be improved, maybe it needs to be dismantled a bit."

O'Brien, who is due to retire next month, has angered the gay community with his conservative stance on homosexuality. He was named "bigot of the year" last year by the rights charity Stonewall.

He recently said that same-sex marriages would be "harmful to the physical, mental and spiritual well-being of those involved" and has long voiced opposition to gay adoption.

- AFP/jc

Read More..

Ramdev trust, govt keep options open over Feb 27 function

SHIMLA: Having taken possession of 28 acres land leased out to Patanjali Yogapeeth at Sadhupul area of Solan district, the Himachal Pradesh government does not want yoga guru Swami Ramdev to hold his function there on February 27. Fearing stiff resistance from supporters of Swami Ramdev, government had planned to impose section 144 in Sadhupul and surrounding areas and had made heavy deployment of police in the area.

Resultantly, Patanjali Yogapeeth officials are now looking for another venue either at Solan or Kandaghat to hold the function. Sources said that people in Sadhupul area were adamant about holding the function there itself, but Patanjali Yogapeeth officials, after getting inputs about imposition of section 144, decided to change the venue to avoid any confrontation with government.

On Saturday, Yogapeeth officials submitted an application to Solan Municipal Council for holding the function at Thodo ground on February 27, but the civic body has not given any assurance to them about granting them permission. As confusion about the venue continues, Yogapeeth officials have kept the option of holding the function at Kandaghat also open, sources said.

State incharge of Patanjali Yogapeeth and Bharat Swabhiman Trust, Lakshmi Dutt Sharma, said that they will finalise the venue by Sunday evening. "We decided not to hold the function at Sadhupul as officials informed us about government decision to impose section 144 in the area. We are now looking for some other venue as we do not want any law and order problem, but we have not got any assurance from the authorities concerned," he said.

Sources said that to stop Patanjali Yogapeeth from obtaining stay from court, the state government planned to file a caveat in the court, while the Yogapeeth is reportedly planning to approach the court on the issue.

The opposition BJP, on its part, has decided to support Swami Ramdev if he launched an agitation on the issue. State BJP president Satpal Singh Satti has said that his party would extend full support if Ramdev starts an agitation to oppose the government move. He said the previous BJP government had allotted the land to Ramdev as setting up a Patanjali Yogapeeth facility in the area would have benefitted residents of surrounding villages immensely. "We condemn the act of Congress government," he said.

Read More..

FDA approves new targeted breast cancer drug

WASHINGTON (AP) — The Food and Drug Administration has approved a first-of-a-kind breast cancer medication that targets tumor cells while sparing healthy ones.

The drug Kadcyla from Roche combines the established drug Herceptin with a powerful chemotherapy drug and a third chemical linking the medicines together. The chemical keeps the cocktail intact until it binds to a cancer cell, delivering a potent dose of anti-tumor poison.

Cancer researchers say the drug is an important step forward because it delivers more medication while reducing the unpleasant side effects of chemotherapy.

"This antibody goes seeking out the tumor cells, gets internalized and then explodes them from within. So it's very kind and gentle on the patients — there's no hair loss, no nausea, no vomiting," said Dr. Melody Cobleigh of Rush University Medical Center. "It's a revolutionary way of treating cancer."

Cobleigh helped conduct the key studies of the drug at the Chicago facility.

The FDA approved the new treatment for about 20 percent of breast cancer patients with a form of the disease that is typically more aggressive and less responsive to hormone therapy. These patients have tumors that overproduce a protein known as HER-2. Breast cancer is the second most deadly form of cancer in U.S. women, and is expected to kill more than 39,000 Americans this year, according to the National Cancer Institute.

The approval will help Roche's Genentech unit build on the blockbuster success of Herceptin, which has long dominated the breast cancer marketplace. The drug had sales of roughly $6 billion last year.

Genentech said Friday that Kadcyla will cost $9,800 per month, compared to $4,500 per month for regular Herceptin. The company estimates a full course of Kadcyla, about nine months of medicine, will cost $94,000.

FDA scientists said they approved the drug based on company studies showing Kadcyla delayed the progression of breast cancer by several months. Researchers reported last year that patients treated with the drug lived 9.6 months before death or the spread of their disease, compared with a little more than six months for patients treated with two other standard drugs, Tykerb and Xeloda.

Overall, patients taking Kadcyla lived about 2.6 years, compared with 2 years for patients taking the other drugs.

FDA specifically approved the drug for patients with advanced breast cancer who have already been treated with Herceptin and taxane, a widely used chemotherapy drug. Doctors are not required to follow FDA prescribing guidelines, and cancer researchers say the drug could have great potential in patients with earlier forms of breast cancer

Kadcyla will carry a boxed warning, the most severe type, alerting doctors and patients that the drug can cause liver toxicity, heart problems and potentially death. The drug can also cause severe birth defects and should not be used by pregnant women.

Kadcyla was developed by South San Francisco-based Genentech using drug-binding technology licensed from Waltham, Mass.-based ImmunoGen. The company developed the chemical that keeps the drug cocktail together and is scheduled to receive a $10.5 million payment from Genentech on the FDA decision. The company will also receive additional royalties on the drug's sales.

Shares of ImmunoGen Inc. rose 2 cents to $14.32 in afternoon trading. The stock has ttraded in a 52-wek range of $10.85 to $18.10.

Read More..

Jodi Arias' Friends Believe in Her Innocence

Accused murderer Jodi Arias believes she should be punished, but hopes she will not be sentenced to death, two of her closest friends told ABC News in an exclusive interview.

Ann Campbell and Donavan Bering have been a constant presence for Arias wth at least one of them sitting in the Phoenix, Ariz., courtroom along with Arias' family for almost every day of her murder trial. They befriended Arias after she first arrived in jail and believe in her innocence.

Arias admits killing her ex-boyfriend Travis Alexander and lying for nearly two years about it, but insists she killed Alexander in self defense. She could face the death penalty if convicted of murder.

Jodi Arias Testimony: Prosecution's Cross-Examination Watch Video

Jodi Arias Remains Calm Under Cross-Examination Watch Video

Jodi Arias Doesn't Remember Stabbing Ex-Boyfriend Watch Video

Nevertheless, she is aware of the seriousness of her lies and deceitful behavior.

The women told ABC News that they understand that Arias needs to be punished and Arias understands that too.

"She does know that, you know, she does need to pay for the crime," Campbell said. "But I don't want her to die, and I know that she has so much to give back."

Catching Up on the Trial? Check Out ABC News' Jodi Arias Trial Coverage

The lies that Arias admits she told to police and her family have been devastating to her, Bering said.

""She said to me, 'I wish I didn't have to have lied. That destroyed me,'" Donovan said earlier this week. "Because now when it's so important for her to be believed, she has that doubt. But as she told me on the phone yesterday, she goes, 'I have nothing to lose.' So all she can do is go out there and tell the truth."

During Arias' nine days on the stand she has described in detail the oral, anal and phone sex that she and Alexander allegedly engaged in, despite being Mormons and trying to practice chastity. She also spelled out in excruciating detail what she claimed was Alexander's growing demands for sex, loyalty and subservience along with an increasingly violent temper.

Besides her two friends, Arias' mother and sometimes her father have been sitting in the front row of the courtroom during the testimony. It's been humiliating, Bering said.

"She's horrified. There's not one ounce of her life that's not out there, that's not open to the public. She's ashamed," she said.

Read More..

Abe vows to revive Japanese economy, sees no escalation with China

WASHINGTON (Reuters) - Japanese Prime Minister Shinzo Abe told Americans on Friday "I am back and so is Japan" and vowed to get the world's third biggest economy growing again and to do more to bolster security and the rule of law in an Asia roiled by territorial disputes.

Abe had firm words for China in a policy speech to a top Washington think-tank, but also tempered his remarks by saying he had no desire to escalate a row over islets in the East China Sea that Tokyo controls and Beijing claims.

"No nation should make any miscalculation about firmness of our resolve. No one should ever doubt the robustness of the Japan-U.S. alliance," he told the Center for Strategic and International Studies.

"At the same time, I have absolutely no intention to climb up the escalation ladder," Abe said in a speech in English.

After meeting U.S. President Barack Obama on his first trip to Washington since taking office in December in a rare comeback to Japan's top job, he said he told Obama that Tokyo would handle the islands issue "in a calm manner."

"We will continue to do so and we have always done so," he said through a translator, while sitting next to Obama in the White House Oval Office.

Tension surged in 2012, raising fears of an unintended military incident near the islands, known as the Senkaku in Japan and the Diaoyu in China. Washington says the islets fall under a U.S.-Japan security pact, but it is eager to avoid a clash in the region.

Abe said he and Obama "agreed that we have to work together to maintain the freedom of the seas and also that we would have to create a region which is governed based not on force but based on an international law."

Abe, whose troubled first term ended after just one year when he abruptly quit in 2007, has vowed to revive Japan's economy with a mix of hyper-easy monetary policy, big spending, and structural reform. The hawkish leader is also boosting Japan's defense spending for the first time in 11 years.

"Japan is not, and will never be, a tier-two country," Abe said in his speech. "So today ... I make a pledge. I will bring back a strong Japan, strong enough to do even more good for the betterment of the world."

'ABENOMICS' TO BOOST TRADE

The Japanese leader stressed that his "Abenomics" recipe would be good for the United States, China and other trading partners.

"Soon, Japan will export more, but it will import more as well," Abe said in the speech. "The U.S. will be the first to benefit, followed by China, India, Indonesia and so on."

The United States and Japan agreed language during Abe's visit that could set the stage for Tokyo to join negotiations soon on a U.S.-led regional free trade agreement known as the Trans-Pacific Partnership.

In a carefully worded statement following the meeting between Obama and Abe, the two countries reaffirmed that "all goods would be subject to negotiations if Japan joins the talks with the United States and 10 other countries.

At the same time, the statement envisions a possible outcome where the United States could maintain tariffs on Japanese automobiles and Japan could still protect its rice sector.

"Recognizing that both countries have bilateral trade sensitivities, such as certain agricultural products for Japan and certain manufactured products for the United States, the two governments confirm that, as the final outcome will be determined during the negotiations, it is not required to make a prior commitment to unilaterally eliminate all tariffs upon joining the TPP negotiations," the statement said.

Abe repeated that Japan would not provide any aid for North Korea unless it abandoned its nuclear and missile programs and released Japanese citizens abducted decades ago to help train spies.

Pyongyang admitted in 2002 that its agents had kidnapped 13 Japanese in the 1970s and 1980s. Five have been sent home, but Japan wants better information about eight who Pyongyang says are dead and others Tokyo believes were also kidnapped.

Abe also said he hoped to have a meeting with new Chinese leader Xi Jinping, who takes over as president next month, and would dispatch Finance Minister Taro Aso to attend the inauguration of incoming South Korean President Park Geun-hye next week.

(Additional reporting by Jeff Mason and Doug Palmer; Editing by David Brunnstrom and Paul Simao)

Read More..

US state sounds alarm over nuclear waste leaks

LOS ANGELES - At least six tanks containing radioactive waste in the US state of Washington are leaking, the state said Friday, urging more federal help to clean up a site used to make Cold War-era bombs.

Washington governor Jay Inslee said that the extent of the leaks at the Hanford site -- which first produced fuel for nuclear bombs in World War II and closed down 25 years ago -- was "disturbing."

"There is no immediate or near-term health risk associated with these newly discovered leaks, which are more than five miles from the Columbia River," he said, after meeting US Energy Secretary Steven Chu in Washington DC.

"But nonetheless this is disturbing news for all Washingtonians," he said.

He noted that Chu, the outgoing US energy secretary, told him a week ago that only one tank was leaking, but admitted "his department did not adequately analyze data it had that would have shown the other tanks that are leaking."

"This certainly raises serious questions about the integrity of all 149 single-shell tanks with radioactive liquid and sludge at Hanford.

"I believe we need a new system for removing waste from these aging tanks, and was heartened to hear that the Department of Energy is looking at options for accelerating that process."

The Hanford nuclear site, 300km southeast of Seattle, was used to produce plutonium for the bomb that brought an end to World War II.

Output grew after 1945 to meet the challenges of the Cold War, but the last reactor closed down in 1987. Its website says: "Weapons production processes left solid and liquid wastes that posed a risk to the local environment."

Millions of gallons of leftover waste is contained in 177 tanks at the site, according to the Department of Energy, which in 1989 agreed a deal with Washington state authorities to clean up the Hanford site.

Governor Inslee urged federal authorities to act quickly to ensure that looming US budget constraints do not jeopardize extra measures for the nuclear waste site.

"Secretary Chu has a long-standing personal commitment to the clean-up of Hanford. He has assured me he will do all he can to address the issue of the leaking tanks," he said.

But he added: "Frankly, the state Department of Ecology is not convinced that current storage is adequate to meet legal and regulatory requirements.

"With potential sequestration and federal budget cuts looming, we need to be sure the federal government maintains its commitment and legal obligation to the clean-up of Hanford."

A Department of Energy spokesman, Lindsey Geisler, confirmed that "there are six tanks at the Hanford site...including the one announced last week, that show declining levels of fluid."

"There is no immediate public health risk. The Department is working with the State of Washington and other key stakeholders to address the issues associated with these tanks," he added.

Details of exactly what kind of waste was involved were not immediately available.

A spokeswoman for governor Inslee, Jaime Smith, said: "It's nuclear waste. Different tanks have slightly different kinds of waste that they're holding. We're not clear yet on exactly what has been leaking for how long."

Washington state authorities hoped for more information about the leaking tanks soon, the spokeswoman told AFP.

"The Department of Energy has committed to try and get us more information pretty quickly, hopefully within the next week or so. So we should have more information soon," she said.

- AFP/ir

Read More..

Hyderabad, hotbed of home-grown terror, under lens

NEW DELHI: For the veterans of security establishment the bomb blasts have revived concerns about the critical nature of Hyderabad and surroundings in the growth of home-grown terrorism in India.

Officials point out that Hyderabad has been intricately linked to the growth of the present phase of domestic terrorism. When the first definite information about Muslim youth going to Pakistan for terror camps emerged more than a decade ago, with Hyderabad resident Shahid Bilal as a key figure, the government was alarmed at the highest levels. Once India confirmed that over 60 youth have gone across to Pakistan from Andhra Pradesh and Karnataka in 2005-06 the issue was taken up with Bangladeshi and Nepalese governments because most of them were going via either of these countries.

"Even if the bombers are from outside, they have received local logistical support," says one official. "There is a history here," he says about Hyderabad's brush with blasts as well as with fringe sympathisers.

A day before the twin blasts, the National Investigation Agency (NIA) had, in fact, filed its first charge sheet in the case of Bangalore-Hubli-Nanded terror module run from Saudi Arabia by LeT-HuJI handlers. One name among the 12 accused stood out: Obaidur Rehman. The 26-year-old Hyderabad resident is the nephew of Maulana Mohammed Naseeruddin, a radical preacher presently languishing in a Gujarat jail in connection with the murder of Gujarat home minister Haren Pandya.

The charge sheet also mentioned the man handling the group from Saudi Arabia as Farhatullah Ghori, maternal uncle of slain HuJI operative Shahid Bilal. Both belong to Hyderabad.

The blasts that followed the charge sheet have only come as a grim reminder of the Andhra Pradesh capital having become a favourite recruiting ground for terror groups. In fact, the city has been in terror crosshairs for close to a decade and a half providing strong base to both LeT and HuJI.

According to intelligence agencies, Hyderabad first came on terror radar in late '90s with several radical religious organizations becoming a springboard to youth taking to terror. While there was an entrenched sense of victimhood and injustice post Babri masjid demolition among Muslims in the state, their anger was first organized and harnessed by Mohammed Abdul Shahid alias Shahid Bilal under aegis of HuJI.

The first effects of this endeavor manifested itself in the terror attack on the office of Hyderabad Special Task Force in 2003. Bilal's maternal uncle Farhatullah Ghori's name prominently cropped up in the investigations. He was also a suspect in the Akshardham Temple attack in Gujarat in 2002.

Following this, Bilal was found to be instrumental in conducting several blasts across south India between 2004 and 2007. During this period he also helped 26/11 accused and LeT operative Zabiuddin Ansari alias Abu Jundal escape to Pakistan via Bangladesh along with his associate Fayyaz Kagzi after the 2006 Aurangabad arms haul in Maharashtra. In October 2007, Bilal was himself killed in Karachi along with his brother Samad. However, sources say, he has five more brothers who are in Pakistan and elsewhere. And the network he has left behind across India, Pakistan and Saudi Arabia keeps recruiting people for Jihadi activities.

In 2008, Maulana Naseeruddin's son, Riyazuddin Nasir, was arrested in Dharwad, Karnataka for planning to carry out terror strikes in the state. In 2012, with Obaidur Rehman's arrest in the Bangalore terror module, the city again struggled to shake off the terror tag.

Read More..

FDA approves new targeted breast cancer drug

WASHINGTON (AP) — The Food and Drug Administration has approved a first-of-a-kind breast cancer medication that targets tumor cells while sparing healthy ones.

The drug Kadcyla from Roche combines the established drug Herceptin with a powerful chemotherapy drug and a third chemical linking the medicines together. The chemical keeps the cocktail intact until it binds to a cancer cell, delivering a potent dose of anti-tumor poison.

Cancer researchers say the drug is an important step forward because it delivers more medication while reducing the unpleasant side effects of chemotherapy.

"This antibody goes seeking out the tumor cells, gets internalized and then explodes them from within. So it's very kind and gentle on the patients — there's no hair loss, no nausea, no vomiting," said Dr. Melody Cobleigh of Rush University Medical Center. "It's a revolutionary way of treating cancer."

Cobleigh helped conduct the key studies of the drug at the Chicago facility.

The FDA approved the new treatment for about 20 percent of breast cancer patients with a form of the disease that is typically more aggressive and less responsive to hormone therapy. These patients have tumors that overproduce a protein known as HER-2. Breast cancer is the second most deadly form of cancer in U.S. women, and is expected to kill more than 39,000 Americans this year, according to the National Cancer Institute.

The approval will help Roche's Genentech unit build on the blockbuster success of Herceptin, which has long dominated the breast cancer marketplace. The drug had sales of roughly $6 billion last year.

Genentech said Friday that Kadcyla will cost $9,800 per month, compared to $4,500 per month for regular Herceptin. The company estimates a full course of Kadcyla, about nine months of medicine, will cost $94,000.

FDA scientists said they approved the drug based on company studies showing Kadcyla delayed the progression of breast cancer by several months. Researchers reported last year that patients treated with the drug lived 9.6 months before death or the spread of their disease, compared with a little more than six months for patients treated with two other standard drugs, Tykerb and Xeloda.

Overall, patients taking Kadcyla lived about 2.6 years, compared with 2 years for patients taking the other drugs.

FDA specifically approved the drug for patients with advanced breast cancer who have already been treated with Herceptin and taxane, a widely used chemotherapy drug. Doctors are not required to follow FDA prescribing guidelines, and cancer researchers say the drug could have great potential in patients with earlier forms of breast cancer

Kadcyla will carry a boxed warning, the most severe type, alerting doctors and patients that the drug can cause liver toxicity, heart problems and potentially death. The drug can also cause severe birth defects and should not be used by pregnant women.

Kadcyla was developed by South San Francisco-based Genentech using drug-binding technology licensed from Waltham, Mass.-based ImmunoGen. The company developed the chemical that keeps the drug cocktail together and is scheduled to receive a $10.5 million payment from Genentech on the FDA decision. The company will also receive additional royalties on the drug's sales.

Shares of ImmunoGen Inc. rose 2 cents to $14.32 in afternoon trading. The stock has ttraded in a 52-wek range of $10.85 to $18.10.

Read More..

Arias Challenged On Pedophilia Claim

Accused murderer Jodi Arias was challenged today by phone records, text message records, and her own diary entries that appeared to contradict her claim that she caught her ex-boyfriend, Travis Alexander, looking at pictures of naked boys.

Arias had said during her testimony that one afternoon in January 2008, she walked in on Alexander masturbating to pictures of naked boys. She said she fled from the home, threw up, drove around aimlessly, and ignored numerous phone calls from Alexander because she was so upset at what she had seen.

The claim was central to the defense's accusation that Alexander was a "sexual deviant" who grew angry and abusive toward Arias in the months after the incident, culminating in a violent confrontation in June that left Alexander dead.

Arias claimed she killed him in self-defense. She could face the death penalty if convicted of murder.

Catching Up on the Trial? Check Out ABC News' Jodi Arias Trial Coverage

Today, prosecutor Juan Martinez, who has been aggressive in questioning witnesses throughout the trial, volleyed questions at her about the claim of pedophilia, asking her to explain why her and Alexander's cell phone records showed five calls back and forth between the pair throughout the day she allegedly fled in horror. Some of the calls were often initiated Arias, according to phone records.

Jodi Arias Doesn't Remember Stabbing Ex-Boyfriend Watch Video

Jodi Arias Murder Trial: Testimony About Ex's Death Watch Video

Arias on Ex-Boyfriend's Death: 'I Don't Remember' Watch Video

She and Alexander also exchanged text messages throughout the afternoon and evening at a time when Arias claims the pedophilia incident occurred. In those messages they discuss logistics of exchanging one another's cars that night. Alexander sends her text messages about the car from a church social event he attended that night that she never mentioned during her testimony.

Arias stuck by her claim that she saw Alexander masturbating to the pictures, and her voice remained steady under increasingly-loud questioning by Martinez.

But Martinez also sparred with Arias on the stand over minor issues, such as when he asked Arias detailed questions about the timing and order of events from that day and Arias said she could not remember them.

"It seems you have problems with your memory. Is this a longstanding thing? Since you started testifying?" Martinez asked.

"No it goes back farther than that. I don't know even know if I'd call it a problem," Arias said.

"How far back does it go? You don't want to call them problems, are they issues? Can we call them issues? When did you start having them?" he asked in rapid succession. "You say you have memory problems, that it depends on the circumstance. Give me the factors that influence that."

"Usually when men like you or Travis are screaming at me," Arias shot back from the stand. "It affects my brain, it makes my brain scramble."

"You're saying it's Mr. Martinez's fault?" Martinez asked, referring to himself in the third person.

"Objection your honor," Arias' attorney finally shouted. "This is a stunt!"

Timeline of the Jodi Arias Trial

Martinez dwelled at one point about a journal entry where Arias wrote that she missed the Mormon baptism of her friend Lonnie because she was having kinky sex with Alexander. He drew attention to prior testimony that she and Alexander used Tootsie Pops and Pop Rocks candy as sexual props.

"You're trying to get across (in the diary entry) that this involved a sexual liaison with Mr. Alexander right?" he asked. "And you're talking about Tootsie Pops and Pop Rocks?"

"That happened also that night," Arias said.

"You were there, enjoying it, the Tootsie Pops and Pop Rocks?" he asked again, prompting a smirk from Arias.

"I enjoyed his attention," Arias said.

Read More..

Uncertainty hangs heavy as Italy braces for elections

ROME: Italy was poised to hold its most important elections in a generation starting on Sunday, as financial markets warned an unclear outcome could plunge the eurozone's third economy back into crisis.

Italians will cast their ballots as they grapple with the longest recession in two decades and several rounds of austerity cuts that have caused deep resentment and could favour a low turnout and a high number of protest votes.

The most likely outcome is a centre-left government led by Democratic Party leader Pier Luigi Bersani, a cigar-chomping former communist with a down-to-earth manner who now espouses broadly pro-market economic views.

But the result is by no means certain and whether Bersani will be able to form a stable coalition is in doubt. Some fear there may have to be another election within months after a reform of a maddeningly complex electoral law.

With everything at stake, the campaign has been remarkably underwhelming, with few rallies and a lot of back-and-forth in television interviews that have provided little or no detail on sometimes extravagant programme promises.

A case in point was Silvio Berlusconi's promise to refund Italians an unpopular property tax levied by Prime Minister Mario Monti's government in a letter that prompted some to queue up to claim their money back immediately.

European capitals and foreign investors will be watching closely as a return to Italy's free-wheeling public finances could spell disaster for the eurozone.

"We believe that a risk exists that after the February 24-25 elections there may be a loss of momentum on important reforms to improve Italian growth prospects," Standard & Poor's ratings agency said in a report this week.

London-based Capital Economics warned that even with a stable governing majority "huge underlying economic problems suggest that it may only be a matter of time before concerns about the public finances begin to build again."

"And a hung parliament might plunge Italy and the eurozone back into crisis rather sooner," the independent economic research company said this week.

Polls open at 0700 GMT on Sunday and close at 1900 GMT. A second day of voting on Monday begins at 0600 GMT and ends at 1400 GMT, after which preliminary results will begin to trickle through late Monday and into Tuesday.

Wild card

The wild card in the election will be Beppe Grillo, a tousle-haired former comedian whose mix of invective and idealism appeals to protest voters fed up with corrupt politicians. He has spoken to packed squares across Italy.

Bersani has said he will follow the course set by Monti, a former high-flying European commissioner roped in to replace the scandal-tainted Berlusconi who was forced to step down in November 2011.

But Bersani will come under immediate pressure to row back on austerity and do more to create jobs in an economy where an already record-high unemployment rate of 11.2 per cent masks far higher joblessness among women and young people.

A Bersani victory is far from a sure thing mainly because of the rapid rise in the polls of Berlusconi, the irrepressible 76-year-old billionaire tycoon who is still in the game even after 20 tumultuous years in Italian politics.

This is the sixth election campaign for Berlusconi, who has been prime minister three times, has survived multiple court cases, sex scandals and diplomatic gaffes.

One recent poll said he was within 2.5 points of catching up with Bersani.

Berlusconi has pursued a populist campaign, intimating that Italy's current social misery can be blamed on a "hegemonic" Germany imposing austerity.

The president of the European Parliament, who was once invited to play the role of a Nazi camp guard by Berlusconi during a speech when he was still prime minister, has warned Italians not to vote for the flamboyant tycoon.

"Berlusconi has already sent Italy into a tailspin with irresponsible government action and personal capers," Martin Schulz told German tabloid Bild, adding that Italy should not lose its new found confidence in Europe.

Several polls indicate that Bersani may score only a half-victory by managing to secure a stable majority in the lower house of parliament, the Chamber of Deputies, but failing to get one in the upper house, the Senate.

That would give Monti, a somewhat staid economics professor who is running as head of an eclectic centrist grouping, a crucial role as a coalition partner and could bring him back into a government with a ministerial posting.

An average of the most recent polls, which cannot be published in the two weeks leading up to the election, would give Bersani 34 per cent, Berlusconi 30 per cent, Grillo 17 per cent and Monti between 10 and 12 per cent of the vote.

Coming after the last polls were made public, Pope Benedict XVI's resignation could boost the church-going Monti and stop Berlusconi as it has drawn away the media attention that the showman tycoon has often relied on.

The run-up to the vote has also been marked by a succession of high-profile corruption inquiries against politicians and business leaders in a period similar to one in the early 1990s that brought down an entire political class.

Monti has said that the storm of scandals marks "the end of an era".

- AFP/ck

Read More..

Thousands flock to annual MP 'bhoot mela' to get exorcised

BETUL: It's a mela with a spirited presence. In Malajpur, a village in Betul district some 300 km from Bhopal, an annual fair is devoted to the exorcising of ghosts. Thousands throng here from Madhya Pradesh, Maharashtra, Rajasthan and even Andhra Pradesh for the month-long 'bhoot pret ka mela' that will make their lives easier.

While exorcism is an old practice in some of India's villages, holding a fair for it is rare. The mela is held in a temple on the first day of Paush Poornima and continues till Basant Panchami. Bhikhari lal Yadav, a priest there explains, "Exorcism here is a centuries-old practice. We hold a samadhi of Guru Deoji sant and every evening, after the prayer, we treat those under the spell of ghosts and evil spirits." Guru Deoji, incidentally, was a Rajput with supernatural powers who was born around 1700 AD. His powers included turning sand to sugar, clay to jaggery and restoring eyesight to the blind. His reputation grew when, during droughts, he made the granaries overflow. After his death, a samadhi was made and for the last two-and-a-half centuries, exorcism has been going on here.

It is mainly women who come here to get rid of evil spirits. Psychiatrists say this is because their mental problems are often ignored by their families till it gets worse and they seem 'possessed'. The treatment is free here and devotees offer jaggery if their wishes are fulfilled. This year, more than 1,000 women were exorcised.

The exorcism starts late in the evening after 'aarti' has been performed. While normal people do a 'parikrama' of the temple anti-clockwise, the 'possessed' walk clockwise. Crowds chant, "Guru Maharaj ki jai" and families bring their ill members one-by-one. Amidst the chanting of mantras and sprinkling of holy water, the women become hysterical and flay about wildly before collapsing. Earlier, the priests would wield brooms during the rituals but that's a practice of the past.

Sunita, a Class IX student from Rampur village in Chhindwara district, is one of those believed to have benefited from this ritual. A relative of hers says, " One day, she suddenly fell unconscious and we were convinced she was possessed by an evil spirit. After a session of exorcism, she has started behaving normally."

Families of others too say their wards have got better. However, Rahul Sharma, a clinical psychologist from Gandhi Medical College, Bhopal, says the psyche of those assembled at Malajpur can be termed as a "hysterical" and says that conventional treatments such as psychotherapy, sociotherapy and medicines can also cure this problem.

Such blind practices are being combated, says S R Azad, general secretary of MP Vigyan Sabha. "We often do awareness camps and communicate to the villagers through science. The government should discourage this kind of superstition where poor villagers are exploited."

That's easier said than done.

Read More..

APNewsBreak: Govs to hear Oregon health care plan

SALEM, Ore. (AP) — Oregon Gov. John Kitzhaber will brief other state leaders this weekend on his plan to lower Medicaid costs, touting an overhaul that President Barack Obama highlighted in his State of the Union address for its potential to lower the deficit even as health care expenses climb.

The Oregon Democrat leaves for Washington, D.C., on Friday to pitch his plan that changes the way doctors and hospitals are paid and improves health care coordination for low income residents so that treatable medical problems don't grow in severity or expense.

Kitzhaber says his goal is to win over a handful of other governors from each party.

"I think the politics have been dialed down a couple of notches, and now people are willing to sit down and talk about how we can solve the problem" of rising health care costs, Kitzhaber told The Associated Press in a recent interview.

Kitzhaber introduced the plan in 2011 in the face of a severe state budget deficit, and he's been talking for two years about expanding the initiative beyond his state. Now, it seems he's found people ready to listen.

Hospital executives from Alabama visited Oregon last month to learn about the effort. And the U.S. Department of Health and Human Services announced Thursday that it's giving Oregon a $45 million grant to help spread the changes beyond the Medicaid population and share information with other states, making it one of only six states to earn a State Innovation Model grant.

Kitzhaber will address his counterparts at a meeting of the National Governors Association. His talk isn't scheduled on the official agenda, but a spokeswoman confirmed that Kitzhaber is expected to present.

"The governors love what they call stealing from one another — taking the good ideas and the successes of their colleagues and trying to figure out how to apply that in their home state," said Matt Salo, director of the National Association of Medicaid Directors.

There's been "huge interest" among other states in Oregon's health overhaul, Salo said, not because the concepts are brand new, but because the state managed to avoid pitfalls that often block health system changes.

Kitzhaber persuaded state lawmakers to redesign the system of delivering and paying for health care under Medicaid, creating incentives for providers to coordinate patient care and prevent avoidable emergency room visits. He has long complained that the current financial incentives encourage volume over quality, driving costs up without making people healthier.

Obama, in his State of the Union address this month, suggested that changes such as Oregon's could be part of a long-term strategy to lower the federal debt by reigning in the growing cost of federally funded health care.

"We'll bring down costs by changing the way our government pays for Medicare, because our medical bills shouldn't be based on the number of tests ordered or days spent in the hospital — they should be based on the quality of care that our seniors receive," Obama said.

The Obama administration has invested in the program, putting up $1.9 billion to keep Oregon's Medicaid program afloat over the next five years while providers make the transition to new business models and incorporate new staff and technology.

In exchange, though, the state has agreed to lower per-capita health care cost inflation by 2 percentage points without affecting quality.

The Medicaid system is unique in each state, and Kitzhaber isn't suggesting that other states should adopt Oregon's specific approach, said Mike Bonetto, Kitzhaber's health care policy adviser. Rather, he wants governors to buy into the broad concept that the delivery system and payment models need to change.

That's not a new theory. But Oregon has shown that under the right circumstances massive changes to deeply entrenched business models can gain wide support.

What Oregon can't yet show is proof the idea is working — that it's lowering costs without squeezing on the quality or availability of care. The state is just finishing compiling baseline data that will be used as a basis of comparison.

One factor driving the Obama administration's interest in Oregon's success is the president's health care overhaul. Under the Affordable Care Act, millions more Americans will join the Medicaid rolls after Jan. 1, and the health care system will have to be able to absorb the influx of patients in a logistically and financially sustainable way.

The federal government will pay 100 percent of the costs for those additional patients in the first three years before scaling back to 90 percent in 2020 and beyond.

"There are a lot of governors who are facing the same challenges we're facing in Oregon," Kitzhaber said. "They recognize that the cost of health care is something they're going to have to get their arms around."

Read More..

Sony bills coming PS4 console as future of gaming

NEW YORK: Sony unveiled a new-generation PlayStation 4 (PS4) system on Wednesday and laid out its vision for the "future of gaming" in a world rich with mobile gadgets and play streamed from the Internet cloud.

At a press event in New York, computer entertainment unit chief Andrew House said PS4 "represents a significant shift from thinking of PlayStation as a box or console to thinking of the PlayStation 4 as a leading place for play."

PS4 was designed to get to know players, ideally to the point of being able to predict which games people will buy and have them pre-loaded and ready to go.

It also allows live streaming of gameplay in real-time, letting friends virtually peer over one another's shoulders and even letting game makers to act as "directors" guiding players along.

Sony has also given a "green light" to building "the most powerful network for gaming in the world", according to David Perry, chief of Gaikai cloud gaming company purchased last year by Sony.

Gaikai specialises in letting people play video games streamed from the Internet "cloud" instead of buying titles on disks popped into consoles or computers.

"By combining PlayStation 4, PlayStation Network and social platforms, our vision is to create the first social network with meaning dedicated to games," Perry said during the event.

A button on the PS4 controller will let players instantly stream in-game action to friends in real time, and even allow someone to transfer control to more capable allies when stuck, according to Perry.

He expressed a vision of letting people access and play video games old or new on the Internet using PS4, smartphones, tablets or PS Vita handheld devices.

"We are exploring opportunity enabled by cloud technology with a long-term vision of making PlayStation technology available on any device," Perry said.

"This would fundamentally change the concept of game longevity, making any game new or old available to get up and running on any device, anywhere."

Sony needs to adapt to changing lifestyles while not alienating video game lovers devoted to its hardware.

Low-cost or free games on smartphones or tablet computers are increasing the pressure on video game companies to deliver experiences worth players' time and money.

With the press event still in progress, Sony had yet to indicate availability or pricing for the PS4. New-generation consoles are typically priced in the $400 to $500 range, and blockbuster game titles hit the market at $60 each.

-AFP/gn

Read More..

Jallianwala Bagh massacre: David Cameron's apology that wasn't?

NEW DELHI: David Cameron's statement on the 1919 Jallianwala Bagh massacre, marking it as a "deeply shameful event" in British history but stopping short of a full apology, has not impressed historians.

Mushirul Hasan, directorgeneral of the National Archives, says, "The present generation is not necessarily responsible for mistakes of the past. By apologizing for what General Dyer did, Cameron has set a bad precedent. Now others will demand apologies for past acts of belligerence. There'll be no end to this. The past should be interpreted in that context, not outside it. Such an apology, which obviously has other motives, is not necessarily a good thing."

Writer William Dalrymple agrees for different reasons. "It's meaningless to apologize for what you have no control over. It makes sense if the Congress apologized for 1984, Modi for Gujarat, Blair for Iraq. It was actually a good move for Cameron not to apologize fully — that would've seemed very cynical when you've arrived with a trade delegation. But what Cameron can do is teach the British more about the empire. My children at school have learnt about Tudor England, the Nazis, wars in Europe, but nothing in comparison about the empire. The British are simply unaware of the empire's good — like the Indian civil service's integrity — or its bad, like the terrifying killings of 1858 in north India, compared to which Jallianwala Bagh was a sideshow. The British don't know enough about a period which was much longer and more radically important in its global effects than Nazi Germany."

Current efforts to revamp history-teaching aren't good enough, Dalrymple feels. "I believe Cameron's interested in getting Niall Ferguson on this. Niall's a thorough historian and a very clever and amusing gadfly — but he's also the most pro-empire voice in academia. We need more neutral efforts to educate the British, so they can squarely face the bad parts of this period."

Historian Dilip Simeon feels the British are not the only ones who should confront an unjust past. "The fact that it took nearly 100 years for a British PM to apologize is a commentary in itself," Simeon says. "But we're in no position to look down on the Brits. Countless Indians have been killed in communal riots but no one's ever passed a resolution of regret in Parliament. I take a dim view of British sentiments now but I also ask — how long will it take us?"

Jallianwala Bagh massacre: A timeline

Read More..

Agency checks water after body found in hotel tank

LOS ANGELES (AP) — British tourist Michael Baugh and his wife said water had only dribbled out of the taps at the downtown Cecil Hotel for days.

On Tuesday, after showering, brushing their teeth and drinking some of the tap water, they headed down to the lobby and found out why.

The body of a Canadian woman had been discovered at the bottom of one of four cisterns on the roof of the historic hotel near Skid Row. The tanks provide water for hotel taps and would have been used by guests for washing and drinking.

"The moment we found out, we felt a bit sick to the stomach, quite literally, especially having drank the water, we're not well mentally," Michael Baugh, 27, said.

Los Angeles County Department of Public Health officials issued a do-not-drink order Tuesday while its lab analyzes the water, said Terrance Powell, a director coordinating the department's response. The disclosure contradicts a previous police statement that the water had been deemed safe. Results of the testing were expected by Thursday.

Powell said the water was also used for cooking in the hotel; a coffee shop in the hotel would remain closed and has been instructed to sanitize its food equipment before reopening.

"Our biggest concern is going to be fecal contamination because of the body in the water," Powell said. He said the likelihood of contamination is "minimal" given the large amount of water the body was found in, but the department is being extra cautious.

Powell said the hotel hired a water treatment specialist after the department required it to do so to disinfect its plumbing lines.

A call to the hotel was not returned.

The remains of Elisa Lam, 21, were found by a maintenance worker at the 600-room hotel that charges $65 a night after guests complained about the low water pressure.

Police detectives were working to determine if her death was the result of foul play or an accident.

LAPD Sgt. Rudy Lopez called it suspicious and said a coroner's investigation will determine Lam's cause of death.

Before she died, hotel surveillance footage showed Lam inside an elevator pushing buttons and sticking her head out the doors, looking in both directions. She was later found in the water tank.

Lam, of Vancouver, British Columbia, traveled alone to Los Angeles on Jan. 26 and was last seen five days later by workers at the hotel.

Lopez said the hotel has four cisterns on its roof that are each about 10 feet tall, 4.5 feet wide and hold at least 1,000 gallons of water pumped up from city pipes.

Lam's body was found Tuesday morning at the bottom of one cistern that was about three-quarters full of water, Lopez said.

The opening at the top of the cistern is too small to accommodate firefighters and equipment, so they had to cut a hole in the storage tank to recover Lam's body.

The cisterns are on a platform at least 10 feet above the roof.

To get to the tanks, someone would have to go to the top floor then take a staircase with a locked door and emergency alarm preventing roof access.

Another ladder would have to be taken to the platform and a person would have to climb the side of the tank.

Lopez said there are no security cameras on the roof.

Lam intended to travel to Santa Cruz, about 350 miles north of Los Angeles. Officials said she tended to use public transportation and had been in touch with her family daily until she disappeared.

The Cecil Hotel was built in the 1920s and refurbished several years ago. The hotel is on Main Street in a part of downtown where efforts at gentrification often conflicts with homelessness and crime. It had once been the occasional home of infamous serial killers such as Richard Ramirez, known as the Night Stalker, and Austrian prison author Jack Unterweger, who was convicted of murdering nine prostitutes in Europe and the U.S., the Los Angeles Times reported.

By noon Wednesday, the Cecil Hotel had relocated 27 rooms used by guests to another hotel, but 11 rooms remained filled, Powell said. Those who chose to remain in the hotel were required to sign a waiver in which they acknowledged being informed of the health risks and were being provided bottled water, Powell said.

Baugh and his wife, who were on their first trip to the U.S., had planned to go to SeaWorld on Wednesday. Instead, they were trying to find a new hotel. Their tour agency placed them in another downtown hotel with a less than sterling reputation, from what they heard.

"We're just going from one dodgy place to another," Baugh said, resigned, "but at least there's water."

___

Tami Abdollah can be reached at http://www.twitter.com/latams. Shaya Tayefe Mohajer contributed to this report.

Read More..

Arias Says Violent Sex Preceded Killing

Jodi Arias and her ex-boyfriend, Travis Alexander,, had increasingly violent sex in which he tied her to his bed, twisted her arm, bent her over a desk for anal sex, and made sex videos with her in the hours leading up to the stabbing and shooting frenzy that left Alexander dead.

It was a day in which Arias, 32, inched closer to telling the court how the killing of Alexander took place, but after several hours of increasingly emotional testimony the court was adjourned until Wednesday.

In her sixth day on the stand, Arias tearfully described the sex-filled hours that led to Alexander's death on June 4, 2008. She is charged with murder for killing her former boyfriend, but claims she was forced to kill him self-defense. She could face the death penalty if convicted.

"He tied me up, (on) the bed. It's not my favorite but it's not unbearable," Arias told the court.

She said he used a kitchen knife in the bathroom to cut the rope to the proper length, but she didn't remember whether he left the knife in the bathroom or brought it back to the nightstand in the bedroom.

"There are a lot gaps that day... a lot of things I don't remember that day," she said.

Arias and Alexander then took graphic sexual photos of one another and made a sex video, both of which Arias said were Alexander's ideas. Arias has girlish braids in the pictures.

But the mood of the afternoon turned, she said, when Alexander became angry over a scratched computer disk of photos she gave him. He threw the CD and Arias said she became "apprehensive" of his rising temper.

"I know he's getting angry because Napoleon [Alexander's dog] got up and left the room and he always leaves the room when he gets mad." she testified.

"I don't know that I was consciously thinking (of violence) but I was more tense. I stood up, went to walk over to him, to rub his back and make sure he was okay," she said. "But he grabbed me on the upper arms, spun me around and grabbed my right arm and twisted it behind my back, and bent me over the desk, and pressed up against me."

Charlie Leight/Pool/The Arizona Republic/AP Photo

Jodi Arias Gives Explicit Details About Doomed Relationship Watch Video

Jodi Arias Murder Trial: Why She Said She Did It Watch Video

Jodi Arias Tells How She Met Ex-Boyfriend on Stand Watch Video

"I was scared he was going to throw me or something, kick me," she continued. "He pressed his groin up against my butt, did a few thrusts and then started pulling my pants down."

The pair then had anal sex, which Arias said pacified Alexander.

"I was very relieved. I felt like we had avoided catastrophe. It could have led to another fight," she said.

Instead of a fight, Alexander, who was 27 and a devout Mormon, and Arias decide to go upstairs and take more nude photos of one another. Arias said she hoped the photos would satisfy Alexander over his frustration with the scratched CD.

Evidence introduced earlier in the trial show that Alexander was killed while Arias was photographing Alexander in the shower.

Catching Up on the Trial? Check Out ABC News' Jodi Arias Trial Coverage

Timeline of the Jodi Arias Trial

Earlier, Arias explained that she wasn't planning to visit Alexander during her roadtrip from her home in California, but was convinced by him to spontaneously take a detour to his house for sex and to hang out.

"The very last time I called Travis it was kind of like, I don't know how to describe it, he had been very sweet and was guilting me and making me feel bad that I was taking this big trip without going to see him," Arias said this afternoon.

"When I called him last time it was just like all right, I'm going," she said. "(Sex) was our thing at that time. I wasn't going to go there, stay the night and not do that."

Arias' attorney, Kirk Nurmi, asked her repeatedly on the stand if Arias brought a gun or knife with her on the roadtrip and to Alexander's house. She said that she did not.

She also denied a series of allegations made by the prosecution that she dyed her hair, rented an inconspicuous car, borrowed gas cans, turned off her cell phone, and switched money around her bank accounts as she left for Alexander's house because she was planning to murder him when she got there.

Arias said that her hair remained the same color, auburn-brown, throughout May and June, that she rented a car because her own car was not stable enough for highway travel, that she requested a white car instead of a red one because police pull red ones over more often, and that she transferred money to a business banking account for a tax write-off to classify it as a business trip.

The testimony about the road trip and Arias' planning could be key to the jury as they decide whether the killing was pre-meditated, as the prosecution claims. Arias could face the death penalty if convicted of murder with aggravating factors such as pre-meditation.

Arias said that she "didn't sleep at all last night" before testifying about the dramatic incident today. Her comment was stricken from the record.

Arias also described a barrage of threatening text messages sent by Alexander in which he told her he would exact "revenge" on her soon and called her a "sociopath."

She told the court that Alexander's temper would make her "cower."

The messages show a growing discord between the pair in April 2008, less than two months before Arias killed Alexander.

Read More..

Syria "Scud-type" missile said to kill 20 in Aleppo

AMMAN (Reuters) - A Syrian missile killed at least 20 people in a rebel-held district of Aleppo on Tuesday, opposition activists said, as the army turns to longer-range weapons after losing bases in the country's second-largest city.

The use of what opposition activists said was a large missile of the same type as Russian-made Scuds against an Aleppo residential district came after rebels overran army bases over the past two months from which troops had fired artillery.

As the uprising against President Bashar al-Assad, now a civil war, nears its two-year mark, rebels also landed three mortar bombs in the rarely-used presidential palace compound in the capital Damascus, opposition activists said on Tuesday.

The United Nations estimates 70,000 people have been killed in the conflict between largely Sunni Muslim rebels and Assad's supporters among his minority Alawite sect. An international diplomatic deadlock has prevented intervention, as the war worsens sectarian tensions throughout the Middle East.

A Russian official said on Tuesday that Moscow, which is a long-time ally of Damascus, would not immediately back U.N. investigators' calls for some Syrian leaders to face the International Criminal Court for war crimes.

Moscow has blocked three U.N. Security Council resolutions that would have increased pressure on Assad.

Casualties are not only being caused directly by fighting, but also by disruption to infrastructure and Syria's economy.

An estimated 2,500 people in a rebel-held area of northeastern Deir al-Zor province have been infected with typhoid, which causes diarrhea and can be fatal, due to drinking contaminated water from the Euphrates River, the World Health Organization (WHO) said on Tuesday.

"There is not enough fuel or electricity to run the pumps so people drink water from the Euphrates which is contaminated, probably with sewage," the WHO representative in Syria, Elisabeth Hoff, told Reuters by telephone.

The WHO had no confirmed reports of deaths so far.

BURIED UNDER RUBBLE

In northern Aleppo, opposition activists said 25 people were missing under rubble of three buildings hit by a several-meter-long missile. They said remains of the weapon showed it to be a Scud-type missile of the type government forces increasingly use in Aleppo and in Deir a-Zor.

NATO said in December Assad's forces fired Scud-type missiles. It did not specify where they landed but said their deployment was an act of desperation.

Bodies were being gradually dug up, Mohammad Nour, an activist, said by phone from Aleppo.

"Some, including children, have died in hospitals," he said.

Video footage showed dozens of people scouring for victims and inspecting damage. A body was pulled from under collapsed concrete. At a nearby hospital, a baby said to have been dug out from wreckage was shown dying in the hands of doctors.

Reuters could not independently verify the reports.

Opposition activists also reported fighting near the town of Nabak on the Damascus-Homs highway, another route vital for supplying forces in the capital loyal to Assad, whose family has ruled Syria since the 1960s.

Rebels moved anti-aircraft guns into the eastern Damascus district of Jobar, adjacent to the city centre, as they seek to secure recent gains, an activist said.

"The rebels moved truck-mounted anti-aircraft guns to Jobar and are now firing at warplanes rocketing the district," said Damascus activist Moaz al-Shami.

Russian Deputy Foreign Minister Gennady Gatilov told a news conference a U.N. war crimes report, which accuses military leaders and rebels of terrorizing civilians, was "not the path we should follow ... at this stage it would be untimely and unconstructive."

Syria is not party to the Rome Statute that established the ICC and the only way the court can investigate the situation is if it receives a referral from the Security Council, where Moscow is a permanent member.

(Writing by Oliver Holmes; Editing by Jason Webb)

Read More..

Retinal implants clear new hurdle

PARIS: German-designed implants aimed at restoring vision to patients blinded by retinal disease have succeeded in the second phase of trials, researchers reported on Wednesday.

The device was tested for up to nine months among nine people with retinitis pigmentosa, an inherited disease in which light receptors on the back of the eyeball degenerate and eventually cease to function.

"Of the nine patients observed in the study, three patients were able to read letters spontaneously," Retina Implant AG, a nine-year-old technology startup company that invented the device, said in a press release.

"During observation in and outside the laboratory, patients also reported the ability to recognise faces, distinguish objects such as telephones and read signs on doors."

The study appears in Proceedings of the Royal Society B, a journal published by Britain's de-facto academy of sciences.

The device consists of a tiny light-sensitive chip measuring 3mm by 3mm (0.11 x 0.11 inches), which sends electrical signals down the optic nerve to the brain, providing a "diamond-shaped" black-and-white image with a field of 15 degrees.

Attached to the retina, the implant is powered via a thin cable which connects to a small coil fitted under a fold of skin behind the ear.

The coil is charged when a handheld battery unit is brought up close to it -- the same principle of wireless charging that is used, for instance, in electrical toothbrushes -- and thus means it can be used outdoors.

The battery unit also has two knobs, enabling the user to adjust the brightness and contrast of the image.

The patients received the implant in one eye, the one with the worst visual function.

One of the nine had to drop out of the experiment after the optic nerve was damaged during the implant operation, and another experienced a buildup in eyeball pressure which was successfully treated with drugs.

New drugs and revolutionary medical devices typically undergo a three-phase process of trials on human volunteers.

The number of patients and the scope of the test gradually widens, in a bid to ensure that the innovation is both safe and effective.

The first trial of the implant, published in 2010, used a cable, rather than wireless technology, to power the device.

There are several other entrants in the field for retinal implants, reflecting big advances in electronic miniaturisation and microsurgery in the past decade.

None claims to be a cure but rather an aid to distinguish between light and darkness and ascertain the shape of objects.

"Although the restoration of vision described here is limited, blind persons with no alternative therapy options regard this type of artificial vision as an improvement in everyday life," the German doctors said.

Last week the US firm Second Sight Medical Products gained US regulatory approval in addition to the green light from Europe for its Argus II retinal prosthesis.

There is also a 24-electrode device made by Bionic Vision Australia, which has so far been tested on one patient.

-AFP/gn

Read More..

US supports India's constructive role in Afghanistan

WASHINGTON: Asserting that the United States and India share a vision of a secure, peaceful, democratic and prosperous Afghanistan, the Obama administration has said it strongly supports the constructive role being played by New Delhi in the war-torn country's ongoing development.

During the just concluded trilateral dialogue involving India and Afghanistan in New Delhi on Tuesday, the US expressed particular appreciation for the former's leading role in developing regional trade and investment.

"The US side expressed particular appreciation for India's leading role in helping to advance opportunities for regional trade and investment - and noted our shared interest in advancing the New Silk Road vision of connectivity between South and Central Asia - with Afghanistan at its core," a State Department spokesperson said on the conclusion of the trilateral dialogue in New Delhi.

Officials from the three countries, the spokesperson said, held in-depth consultations on issues ranging from political and security spheres to trade, commerce and investment.

"The United States and India share a vision of a secure, peaceful, democratic and prosperous Afghanistan. We strongly support the constructive role that India plays in Afghanistan's ongoing development," he said.

The US delegation was led by the assistant secretary of state for South and Central Asia, Robert Blake. The US delegation also included the deputy special representative for Afghanistan and Pakistan, Dan Feldman, for the trilateral dialogue.

This meeting follows the inaugural trilateral consultations held at the Afghan Mission in New York City on September 25, 2012.

Read More..

Drug overdose deaths up for 11th consecutive year

CHICAGO (AP) — Drug overdose deaths rose for the 11th straight year, federal data show, and most of them were accidents involving addictive painkillers despite growing attention to risks from these medicines.

"The big picture is that this is a big problem that has gotten much worse quickly," said Dr. Thomas Frieden, head of the Centers for Disease Control and Prevention, which gathered and analyzed the data.

In 2010, the CDC reported, there were 38,329 drug overdose deaths nationwide. Medicines, mostly prescription drugs, were involved in nearly 60 percent of overdose deaths that year, overshadowing deaths from illicit narcotics.

The report appears in Tuesday's Journal of the American Medical Association.

It details which drugs were at play in most of the fatalities. As in previous recent years, opioid drugs — which include OxyContin and Vicodin — were the biggest problem, contributing to 3 out of 4 medication overdose deaths.

Frieden said many doctors and patients don't realize how addictive these drugs can be, and that they're too often prescribed for pain that can be managed with less risky drugs.

They're useful for cancer, "but if you've got terrible back pain or terrible migraines," using these addictive drugs can be dangerous, he said.

Medication-related deaths accounted for 22,134 of the drug overdose deaths in 2010.

Anti-anxiety drugs including Valium were among common causes of medication-related deaths, involved in almost 30 percent of them. Among the medication-related deaths, 17 percent were suicides.

The report's data came from death certificates, which aren't always clear on whether a death was a suicide or a tragic attempt at getting high. But it does seem like most serious painkiller overdoses were accidental, said Dr. Rich Zane, chair of emergency medicine at the University of Colorado School of Medicine.

The study's findings are no surprise, he added. "The results are consistent with what we experience" in ERs, he said, adding that the statistics no doubt have gotten worse since 2010.

Some experts believe these deaths will level off. "Right now, there's a general belief that because these are pharmaceutical drugs, they're safer than street drugs like heroin," said Don Des Jarlais, director of the chemical dependency institute at New York City's Beth Israel Medical Center.

"But at some point, people using these drugs are going to become more aware of the dangers," he said.

Frieden said the data show a need for more prescription drug monitoring programs at the state level, and more laws shutting down "pill mills" — doctor offices and pharmacies that over-prescribe addictive medicines.

Last month, a federal panel of drug safety specialists recommended that Vicodin and dozens of other medicines be subjected to the same restrictions as other narcotic drugs like oxycodone and morphine. Meanwhile, more and more hospitals have been establishing tougher restrictions on painkiller prescriptions and refills.

One example: The University of Colorado Hospital in Aurora is considering a rule that would ban emergency doctors from prescribing more medicine for patients who say they lost their pain meds, Zane said.

___

Stobbe reported from Atlanta.

___

Online:

JAMA: http://www.jama.ama-assn.org

CDC: http://www.cdc.gov

___

AP Medical Writer Lindsey Tanner can be reached at http://www.twitter.com

Read More..

Nike, Oakley Distance Themselves from Pistorius

Corporate sponsors of Olympic "blade runner" Oscar Pistorius have begun to distance themselves from the sprinter, who is accused of murdering his model girlfriend, Reeva Steenkamp. Pistorius is back to court in South Africa Tuesday morning on murder charges.

Oakley, the eyewear manufacturer, and the sporting goods giant Nike announced today that they would no longer run ads featuring Pistorius, the South African double-amputee who gained worldwide fame for running on carbon-fiber blades.

"In light of the recent allegations, Oakley is suspending its contract with Oscar Pistorius, effective immediately. Our hearts are with the families during this difficult time and we'll continue to follow the developments in this tragic case," Oakley spokeswoman Cheri Quigley said in a statement released this afternoon.

Earlier in the day, Nike said it had "no plans" to use Pistorius in future ad campaigns, according to the Associated Press. Nike had already pulled an Internet ad showing Pistorius starting to sprint with the caption, "I am the bullet in the chamber."

The companies made their announcements shortly after Pistorius' own agent, Peet Van Zyl, said publicly that he expected the sponsors to stick with Pistorius through the legal process.

PHOTOS: Paralympic Champion Charged in Killing

Pistorius will appear in court Tuesday morning for a bail hearing. His attorneys are expected to argue against the charge of premeditated murder.

His family has said the shooting was an accident.

The news comes as more details emerge about the incident on Thursday morning in which Pistorius allegedly shot and killed Steenkamp at his gated home in Pretoria, South Africa.

Bryn Lennon; Gallo Images/Getty Images

Oscar Pistorius Allegedly Fought the Night of Shooting Watch Video

Oscar Pistorius: Possibly Incriminating Information Leaked Watch Video

'Blade Runner' Murder Charges: Family Insist Accidental Shooting Watch Video

News reports in local papers have said that police are investigating whether Pistorius had an anger-management problem that led to the incident. They focused in on a bloodied cricket bat that may have been used when Steenkamp died.

A "shocked" teammate of Oscar Pistorius rebutted the rumors and speculation in South Africa that Pistorius had an anger problem.

Ofentse Mogawane, a sprinter for the South African Olympic team who ran the 400-meter relay with Pistorius in the London summer games last year, said Pistorius had always been genial to him and other people.

Mogawane said he would be in court Tuesday to support his friend.

"Basically, he was a very good guy to us, to the teammates and to most athletes," Mogawane said. "He was a really humble person and I wouldn't say a bad word about him. We never had any kind of clash, never any kind of fight or disagreement or arguing.

"The way Oscar's case was, it shocked me, shocked most of the people who know him. Tomorrow in court I am going to be there to support him. To hear what happened the night of the incident," he said.

"Sometimes when people are angry they cannot control their anger. Something must have happened."

Mogawane, 30, spoke in support of Pistorius after a report in South Africa's City Press newspaper that claimed police were looking into the possibility that a bloody cricket bat found in his bedroom was used before the shooting.

"The way the news has been running around in South Africa, that he is a short-tempered person, a person who has problems with anger management, they just want something to say," Mogawane said. "They don't know Oscar at all. They just want to get interviewed and take pictures. But truly speaking, it's just a lot of speculation."

Mogawane said he had seen Pistorius become angry before, but only in the same way as any other athlete or person.

But the City Press reported Sunday that police are investigating different scenarios involving the bat. Among them is the possibility that the flat-fronted bat was used in a violent argument before the shooting.

The paper also reported that Pistorius might have first shot Steenkamp in the bedroom, and that she possibly fled to the bathroom where she was shot three more times through the door.

When Pistorius' family arrived at the scene before paramedics, they saw him carrying Steenkamp down the stairs and performing mouth-to-mouth resuscitation on her, City Press reported.

Pistorius, who is nicknamed the "blade runner" because of the carbon-fiber blades on which he runs, has canceled all his upcoming racing appearances, his agent said Sunday night.

The decision was made to "allow Oscar to concentrate on the upcoming legal proceedings and to help and support all those involved as they try to come to terms with this very difficult and distressing situation," Van Zyl, of In Site Athlete Management, said in a statement.

Pistorius' father was quoted overnight in the South African paper The Sunday Times saying his countrymen are destroying a national icon.

Read More..

Time to refer Syrian war crimes to ICC: U.N. inquiry

GENEVA (Reuters) - United Nations investigators said on Monday that Syrian leaders they had identified as suspected war criminals should face the International Criminal Court (ICC).

The investigators urged the U.N. Security Council to "act urgently to ensure accountability" for violations, including murder and torture, committed by both sides in an uprising and civil war that has killed about 70,000 people since March 2011.

"Now really it's time ... We have a permanent court, the International Criminal Court, who would be ready to take this case," Carla del Ponte, a former ICC chief prosecutor who joined the U.N. team in September, told a news briefing in Geneva.

But because Syria is not party to the Rome Statute that established the ICC, the only way the court can investigate the situation is if it receives a referral from the Security Council. Russia, Assad's long-standing ally and a permanent veto-wielding member of the council, has opposed such a move.

"We cannot decide. But we pressure the international community to decide because it's time to act," del Ponte said.

Brazilian expert Paulo Pinheiro, who leads the U.N. inquiry set up in 2011, said: "We are in very close dialogue with all the five permanent members and with all the members of the Security Council, but we don't have the key that will open the path to cooperation inside the Security Council."

His team of some two dozen experts is tracing the chain of command in Syria to establish criminal responsibility and build a case for eventual prosecution.

"Of course we were able to identify high-level perpetrators," del Ponte said, adding that these were people "in command responsibility...deciding, organizing, planning and aiding and abetting the commission of crimes".

She said it was urgent for the Hague-based war crimes tribunal to take up cases of "very high officials", but did not identify them, in line with the inquiry's practice.

"We have crimes committed against children, rape and sexual violence. We have grave concerns. That is also one reason why an international body of justice must act because it is terrible."

Del Ponte, who tried former Yugoslav President Slobodan Milosevic at the International Criminal Tribunal for the Former Yugoslavia on war crimes charges, said the ICC prosecutor would need to deepen the investigation on Syria before an indictment could be prepared.

Karen Koning AbuZayd, an American member of the U.N. team, told Reuters it had information pointing to "people who have given instructions and are responsible for government policy, people who are in the leadership of the military, for example".

The inquiry's third roster of suspects, building on lists drawn up in the past year, remains secret. It will be entrusted to U.N. High Commissioner for Human Rights Navi Pillay upon expiry of its mandate at the end of March, the report said.

Pillay, a former ICC judge, said on Saturday Assad should be investigated for war crimes, and called for outside action on Syria, including possible military intervention.

Pinheiro said the investigators would not speak publicly about "numbers, names or levels" of suspects.

SEVEN MASSACRES IDENTIFIED

The investigators' latest report, covering the six months to mid-January, was based on 445 interviews conducted abroad with victims and witnesses, as they have not been allowed into Syria.

"We identified seven massacres during the period, five on the government side, two on the armed opponents' side. We need to enter the sites to be able to confirm elements of proof that we have," del Ponte said.

The U.N. report said the ICC was the appropriate institution for the fight against impunity in Syria. "As an established, broadly supported structure, it could immediately initiate investigations against authors of serious crimes in Syria."

Government forces have carried out shelling and air strikes across Syria including Aleppo, Damascus, Deraa, Homs and Idlib, the 131-page report said, citing corroborating satellite images.

"Government forces and affiliated militias have committed extra-judicial executions, breaching international human rights law. This conduct also constitutes the war crime of murder. Where murder was committed as part of a widespread or systematic attack against a civilian population, with knowledge of that attack, it is a crime against humanity," the report said.

Those forces have targeted bakery queues and funeral processions to spread "terror among the civilian population".

Rebels fighting to topple Assad have also committed war crimes including murder, torture, hostage-taking and using children under age 15 in hostilities, the U.N. report said.

"They continue to endanger the civilian population by positioning military objectives inside civilian areas" and rebel snipers had caused "considerable civilian casualties", it said.

George Sabra, a vice president of the opposition Syrian National Coalition, asked about the U.N. report, told Reuters at a conference in Stockholm: "We condemn all kind of crimes, regardless who did it.

"We can't ignore that some mistakes have been made and maybe still happen right now. But nobody also can ignore that the most criminal file is that of the regime."

(This story has been corrected to fix name of Milosevic tribunal in 11th paragraph)

(Reporting by Stephanie Nebehay; additional reporting by Anna Ringstrom in Stockholm; Editing by Mark Heinrich)

Read More..